ASSIGNMENT 1: BIOPHYSICAL CHEMISTRY

ASSIGNMENTS

1. What roles do water and pH play in the structural and functional stability of biomolecules.

2. Discuss the homeostatic regulation of water and pH in the body fluids of organisms.

3. What is acidosis? Discuss.

4. Discuss water under the following headings:
a) Structure of water
b) Water as a dipole

5. What is the pH value of 2.0 x 10-6 mol/L KOH

6. Derive the Henderson-Hasselbalch equation for a weakly ionizing acid (HA)

7. What is the pH of a solution whose OH- concentration is 4.0 x 10-4 mol/L

8. What is the pH of a solution whose H+ ion concentration is 3.2 x 10-4 mol/L

9. Discuss Sorenson’s definition of pH.

10. Explain why and how water forms hydrogen bonds.